Tuberculosis
Tuberculosis (TB) is a contagious and potentially serious infectious disease caused by the bacterium Mycobacterium tuberculosis. It primarily affects the lungs but can also affect other parts of the body, such as the kidneys, spine, and brain.
TB spreads through the air when an infected individual coughs, sneezes, or speaks, releasing tiny droplets containing the bacteria into the air. When a person inhales these droplets, they can become infected with TB. However, it’s important to note that not everyone infected with the bacteria develops active TB. In many cases, the immune system is able to keep the bacteria in check, causing the infection to remain latent.
Latent TB infection means that the bacteria are present in the body but are inactive and do not cause any symptoms. People with latent TB are not contagious and cannot spread the disease to others. However, if the immune system becomes weakened, such as due to certain medical conditions or medications, latent TB can become active.
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Publication date: Oct 11, 2024 Chemical prospection for the mycelial extract of the fungus Acremonium ...
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Ferroptosis: A new way to intervene in the game between Mycobacterium tuberculosis and macrophages.
Publication date: Oct 11, 2024 Mycobacterium tuberculosis (Mtb), the main pathogen responsible for the high ... -
Identifying risk factors for recurrent multidrug resistant tuberculosis based on patient’s record data from 2016 to 2021: retrospective study.
Publication date: Oct 13, 2024 Globally, the prevalence of multidrug-resistant tuberculosis (MDR-TB) has been increasing ... -
Genome sequencing analysis of the pncA, rpsA and panD genes responsible for pyrazinamide resistance of Mycobacterium tuberculosis from Indonesian isolates.
Publication date: Oct 13, 2024 Developing the most suitable treatment against tuberculosis based on resistance ... -
Understanding the impact of pandemics on long-term medication adherence: directly observed therapy in a tuberculosis treatment cohort pre- and post-COVID-19 lockdowns.
Publication date: Oct 14, 2024 The COVID-19 pandemic negatively impacted tuberculosis (TB) treatment services, including ... -
Drug-resistance characteristics, genetic diversity, and transmission dynamics of multidrug-resistant or rifampicin-resistant Mycobacterium tuberculosis from 2019 to 2021 in Sichuan, China.
Publication date: Oct 14, 2024 Multidrug- or rifampicin-resistant tuberculosis (TB; MDR/RR-TB) is a significant public ... -
Risk factors for non-isolation of patients admitted for pulmonary tuberculosis in a high-incidence département: a single-center retrospective study.
Publication date: Oct 10, 2024 Pulmonary tuberculosis (PT) is an airborne disease, justifying the identification ... -
miR-147-3p in pathogenic CD4 T cells controls chemokine receptor expression for the development of experimental autoimmune diseases.
Publication date: Oct 11, 2024 Incomplete Freund’s adjuvant (IFA) has long been used to trigger ... -
Incidence and predictors of opportunistic infections among HIV-infected children on antiretroviral therapy at public health facilities of Southwest Ethiopia People Regional State, 2023: a multicenter retrospective follow-up study.
Publication date: Oct 11, 2024 Opportunistic infections (OIs) pose a significant threat to children infected ... -
HIV co-infection increases the risk of post-tuberculosis mortality among persons who initiated treatment for drug-resistant tuberculosis.
Publication date: Oct 11, 2024 Little is known regarding the relationship between common comorbidities in ... -
Point-of-care biochemistry for primary healthcare in low-middle income countries: a qualitative inquiry.
Publication date: Oct 11, 2024 Access to essential diagnostics is crucial for primary healthcare (PHC) ... -
Synergistic oral beta-lactam combinations for treating tuberculosis.
Publication date: Oct 11, 2024 The enormous burden of tuberculosis (TB) worldwide is a major ... -
Integrating computational and experimental approaches in discovery and validation of MmpL3 pore domain inhibitors for specific labelling of Mycobacterium tuberculosis.
Publication date: Nov 01, 2024 Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), continues to pose ... -
Rational design and microwave-promoted synthesis of triclosan-based dimers: targeting InhA for anti-mycobacterial profiling.
Publication date: Oct 01, 2024 A set of alkyl-/1H-1,2,3-triazole-based dimers was strategically designed and synthesized ... -
Human Cell Model Aids Understanding of Tuberculosis
Publication date: Oct 12, 2024 Over the course of a week, the monocytes transform into ... -
Childhood tuberculosis outcomes and factors associated with unsuccessful treatment outcomes in selected public hospitals of Lusaka Zambia from 2015 to 2019.
Publication date: Oct 11, 2024 Treatment outcomes of tuberculosis in children are rarely evaluated. Childhood ... -
Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction.
Publication date: Oct 12, 2024 Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is ... -
Molecular and microbiological methods for the identification of nonreplicating Mycobacterium tuberculosis.
Publication date: Oct 01, 2024 Chronic tuberculosis (TB) disease, which requires months-long chemotherapy with multiple ... -
Analyzing nutrition risks and blood biomarkers in hospitalized patients with tuberculosis: Insights from a 2020 hospital-based study.
Publication date: Oct 06, 2024 There exists a bidirectional relationship between tuberculosis (TB) and nutrition, ... -
Diagnostic value of impulse oscillometry in chronic obstructive pulmonary disease: a multicentre, retrospective, observational study.
Publication date: Oct 08, 2024 Diagnosis and assessment of chronic obstructive pulmonary disease (COPD) rely ... -
QT Prolongation Associated with Administration of Bedaquiline, a Novel Anti-Tuberculosis Drug.
Publication date: Oct 08, 2024 Bedaquiline is a diarylquinoline compound that has recently been introduced ...