Tuberculosis
Tuberculosis (TB) is a contagious and potentially serious infectious disease caused by the bacterium Mycobacterium tuberculosis. It primarily affects the lungs but can also affect other parts of the body, such as the kidneys, spine, and brain.
TB spreads through the air when an infected individual coughs, sneezes, or speaks, releasing tiny droplets containing the bacteria into the air. When a person inhales these droplets, they can become infected with TB. However, it’s important to note that not everyone infected with the bacteria develops active TB. In many cases, the immune system is able to keep the bacteria in check, causing the infection to remain latent.
Latent TB infection means that the bacteria are present in the body but are inactive and do not cause any symptoms. People with latent TB are not contagious and cannot spread the disease to others. However, if the immune system becomes weakened, such as due to certain medical conditions or medications, latent TB can become active.
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Publication date: Jan 01, 2025 Globally, over one-third of pulmonary tuberculosis (TB) disease diagnoses are ...
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Comparative Diagnostic Accuracy of ChatGPT-4 and Machine Learning in Differentiating Spinal Tuberculosis and Spinal Tumors.
Publication date: Jan 11, 2025 In clinical practice, distinguishing between spinal tuberculosis (STB) and spinal ... -
The Management of Linezolid-Induced Adverse Events in Shorter and Longer Treatment of Rifampicin-Resistant Tuberculosis.
Publication date: Jan 12, 2025 Linezolid is included in most of the regimens for treatment ... -
Unveiling Pediatric Neurosarcoidosis Mimicking Central Nervous System Tuberculosis: Diagnostic Challenges.
Publication date: Jan 12, 2025 Neurosarcoidosis is a rare chronic inflammatory disease affecting the nervous ... -
Differential substrate preferences IN ACTINOBACTERIAL protein O-MANNOSYLTRANSFERASES and alteration of protein-O-MANNOSYLATION by choice of secretion pathway.
Publication date: Jan 13, 2025 Protein-O-mannosylation (POM) is a form of O-glycosylation that is ubiquitous ... -
Inguinal hernia mesh infections: Chronic challenges, atypical pathogens and lessons in sterilisation.
Publication date: Jan 13, 2025 Chronic mesh infections after inguinal hernia repair present significant clinical ... -
Tuberculous longitudinal extensive transverse myelitis: 2 cases and literature review.
Publication date: Jan 13, 2025 This study aimed to investigate the characteristics, diagnosis, and management ... -
Strong immune responses and robust protection following a novel protein in adjuvant tuberculosis vaccine candidate.
Publication date: Jan 13, 2025 BCG remains the only licensed vaccine for tuberculosis (TB), but ... -
Clinical epidemiology, genetic diversity, and drug susceptibility patterns by whole genome sequencing of Mycobacterium tuberculosis complex isolates in Gabon from 2012 to 2022.
Publication date: Mar 01, 2025 This study aimed to investigate genotypic characteristics and drug resistance ... -
Shorter Treatment Regimens Recommended for Tuberculosis
Publication date: Jan 14, 2025 Use of novel regimens containing bedaquiline, pretomanid, and linezolid with ... -
Risk of SARS-CoV-2 infection and adverse outcomes among vaccinated patients with tuberculosis.
Publication date: Jan 10, 2025 Limited data are available to assess breakthrough SARS-CoV-2 infections, medical ... -
Antimycobacterial activity of luteolin in resistant Mycobacterium tuberculosis isolates and cytotoxicity on L929 cells.
Publication date: Jan 10, 2025 Mycobacterium tuberculosis (M. tuberculosis) bacteria can cause oxidative stress and ... -
Genotypic and phenotypic diversity of Mycobacterium tuberculosis strains from eastern India.
Publication date: Jan 10, 2025 Whole genome sequencing has been used to investigate the genomic ... -
A large geno-spatial cluster of multi-drug resistant tuberculosis outbreak in a western district of Thailand.
Publication date: Jan 10, 2025 The growing issue of drug resistance, particularly multidrug-resistant TB (MDR-TB), ... -
Retrospective Evaluation of Combined Anterior and Posterior Surgery with Autologous Tricortical Iliac and Rib Bone Grafting for Severe Kyphotic Deformity in Thoracic Spinal Tuberculosis.
Publication date: Jan 10, 2025 Spinal tuberculosis is a common cause of spinal deformity and ... -
Efficacy of Xpert MTB/RIF assay in detecting Mycobacterium tuberculosis in samples with different results by smear and culture in a coastal city with high incidence of tuberculosis.
Publication date: Jan 11, 2025 Tuberculosis (TB) is a global problem that seriously jeopardizes human ... -
Engineered Mycobacterium tuberculosis triple-kill-switch strain provides controlled tuberculosis infection in animal models.
Publication date: Jan 10, 2025 Human challenge experiments could accelerate tuberculosis vaccine development. This requires ... -
Enhancing tuberculosis case notifications through mapping sales of medicine in the private sector: a quasi-experimental study in Punjab province, Pakistan.
Publication date: Jan 10, 2025 In Pakistan, almost one-third of people who develop tuberculosis (TB) ... -
A BCG kill switch strain protects against Mycobacterium tuberculosis in mice and non-human primates with improved safety and immunogenicity.
Publication date: Jan 10, 2025 Improved vaccination strategies for tuberculosis are needed. Intravenous (i. v.) ... -
Abnormal expression of miR-668-3p in non-small cell lung cancer patients and its correlation with serum-related tumor markers.
Publication date: Jan 10, 2025 The accuracy and reliability of identified biomarkers in differentiating early ... -
Relating ecological diversity to genetic discontinuity across bacterial species.
Publication date: Jan 10, 2025 Genetic discontinuity represents abrupt breaks in genomic identity among species. ...